Differences | Glycine (native amino acid) | Arginine (mutant amino acid) |
Schematic structure |
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Size | Small in size | Bigger in size |
Charge | Natural in charge | Positively charge and it could make repulsion between the mutant residue and neighboring residues |
Flexibility | Most flexible of all residues | Can abolish this function which it might be necessary for the protein’s function |
Conservation | Highly conserved | Not observed at all, this mean in just some rare cases the mutation might occur without damaging the protein |