| Groups | Treatment | Variation of bruise area (%/control) | |
| Mean | SD | ||
| Control | None | 100.0 | 0.0 |
| Positive control | Treatment | 65.54*** | 2.4 |
| Tested mixture (arnica extract + apigenin) | Treatment | 59.87*** | 3.1 |
| Pretreatment + treatment | 44.4***,aa,b | 8.2 | |