Treatment of OSA

% AHI reduction

Authors

Continuous positive airway pressure (CPAP) treatment [86]

95%

Becker (2003)

Decreaseof bodyweight [87] [88]

76% - 80%

Tuomilehto, (2009, 2014)

Bariatric surgery [89] [90]

29% - 71%

Ashrafian (2014), Bhattacharjee (2013).

Uvulopalatopharyngoplastywithtonsillectomy [91] [92]

19% - 64%

Baradaranfar (2015), Boyd (2013).

System for hypoglossal nerve stimulation [93] [94]

50% - 57%

Eastwood (2011), Certal (2014).

Positional therapy lateral or prone positioning in the treatment of mild to moderate OSA.

Mattress and pillow for prone positioning [95] - [99]

50% - 56%

Mador (2005), Heinzer (2012),

Ravesloot, (2013), Afrashi, (2015),

Bidarian-Moniri (2015).

Mandibular advancementdevices (MADs) [100] [101]

50% - 53%

Mehta A (2001), Levendowski (2007)

Drug therapy: Mirtazapine, uptake Serotonin, Others [102] - [104]

24% - 52 %

Carley (2007), Kraiczi (1999), Mason (2013).

Oral appliances (OAs) are indicated for use in patients with mild to moderate OSA (depends mainly on the balance between the perception of benefit and the side effects) [105] [106]

17% - 50%

Fernandez (2007), Sutherland (2014).

Exercise [107] [108]

11% - 32%

Ashrafian (2014), Kline (2011), Iftikhar (2014).