Covariate

n

OS

PFS

Estimated 5-year survival (%)

Univariate p-value

RR

95% CI

Multivariate p-value

Estimated 5-year survival (%)

Univariate p-value

RR

95% CI

Multivariate p-value

Age

<50 years

13

61.4

0.904

42.1

0.982

≥50 years

13

40.0

34.6

Stage

IB

20

53.8

0.188

35.5

0.597

IIA+IIB

6

40.0

40.0

NAC

Received

15

51.3

0.510

31.4

0.717

Not received

11

(60.0)*

(72.7)*

Adjuvant therapy

Concurrent chemoradiotherapy

9

(57.1)*

0.543

(63.5)*

0.424

Radiotherapy alone

3

100.0

100.0

Chemotherapy alone

14

46.9

25.6

Lymph node metastasis

Negative

13

80.0

0.023

7.21

0.89 - 58.46

0.064

65.6

0.0027

6.47

1.33 - 31.43

0.021

Positive

13

30.0

17.1

Parametrial invasion

Negative

19

54.1

0.158

60.4

0.0158

2.68

0.83 - 8.66

0.099

Positive

7

33.3

0

Surgical margin

Negative

25

52.2

0.207

38.4

0.097

Positive

1

0

0

Maximum tumor diameter

<4 cm

9

60.0

0.259

44.4

0.291

≥4 cm

17

46.2

30.9

LVSI

Negative

13

75.0

0.035

4.41

0.89 - 21.98

0.070

37.7

0.126

Positive

13

25.6

36.1

Deep stromal invasion

Negative

8

83.3

0.371

65.6

0.256

Positive

18

41.9

26.0