All patients

Insulin naïve

Insulin users

Daily dose frequency

Pre-study, n

117

0 (0)

117

Once, n (%)

Twice, n (%)

Thrice, n (%)

29 (24.8)

69 (59.0)

19 (16.2)

0 (0)

0 (0)

0 (0)

29 (24.8)

69 (59.0)

19 (16.2)

Baseline, n

506

390

116

Once, n (%)

Twice, n (%)

Thrice, n (%)

>thrice, n (%)

49 (9.7)

332 (65.6)

124 (24.5)

1 (0.2)

47 (12.1)

273 (70.0)

70 (17.9)

0 (0)

2 (1.7)

59 (50.9)

54 (46.6)

1 (0.9)

Week 24, n

463

362

101

Once, n (%)

Twice, n (%)

Thrice, n (%)

>thrice, n (%)

30 (6.5)

293 (63.3)

135 (29.2)

5 (1.1)

28 (7.7)

241 (66.6)

89 (24.6)

4 (1.1)

2 (2.0)

52 (51.5)

46 (45.5)

1 (1.0)

Insulin dose, U/day

Pre-study^*

48.6 (24.0)

0 (0)

48.6 (24.0)

Baseline^*

43.4 (18.3)

39.2 (15.9)

57.2 (19.0)

Week 24^*

60.2 (24.2)

59.7 (25.5)

62.2 (18.7)

Insulin dose, U/kg

Pre-study^*

0.58 (0.26)

0 (0)

0.58 (0.26)

Baseline^*

0.54 (0.22)

0.49 (0.20)

0.70 (0.24)

Week 24^*

0.76 (0.31)

0.76 (0.33)

0.75 (0.23)