Feature

Pituitary cells

Hepatocytes

K cells

Muscle cells

Fibroblasts

BMSCs

Endodermal Origin

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+

Glucose sensing machinery (i.e. GLUT2 and glucokinase)

+

+

Glucose-responsive promoters

+

+

Target of insulin action

+

+

Regulated secretory pathway (i.e. insulin storage and stimulus-secretion coupling)

+

+

Processing enzymes (i.e. PC1/3 and PC2)

+

+