Factors

n

Cause of death

p

Brain metastasis

Other sites metstasis

(n = 30)

(n = 5)

No.

%

No.

%

Age (mean)

56.9 (30.8 - 82.3)

57.1 (49.7 - 63.6)

0.96

Pathological type

Ductal carcinoma

28

23

76.7

5

100.0

0.11

Other

7

7

23.3

0

0.0

Nuclear grade

1/2

19

15

65.2

4

80.0

0.50

3

9

8

34.8

1

20.0

Estrogen receptor

Negative

25

23

76.7

2

40.0

0.06

Positive

10

7

23.3

3

60.0

HER-2/NEU

Negative

14

12

40.0

2

30.0

1.00

Positive

21

18

60.0

3

70.0

Tumor size

T1

4

3

9.7

1

10.0

0.54

T2-4

31

27

90.3

4

90.0

Lymph node metastasis

Negative

10

9

10.0

1

20.0

0.64

Positive

25

21

90.0

4

80.0

Stage

2

17

15

50.0

2

40.0

0.23

3

12

9

30.0

3

60.0

4

6

6

20.0

0

0.0

Number of brain metastasis

1

9

7

23.3

2

40.0

0.44

1<

26

23

76.7

3

60.0

ECOG PS

0 - 1

16

14

46.7

2

40.0

0.78

2 - 4

19

16

53.3

3

60.0

Therapy of brain metastasis

Whole brain radiotherapy

+

31

27

90.0

4

80.0

0.54

4

3

30.0

1

20.0

Tumorectomy

+

2

0

0.0

2

40.0

0.003

33

30

100.0

3

60.0

Systemic therapy

+

16

13

43.3

3

60.0

0.49

19

17

56.7

2

20.0