MicroRNAs

Target Genes/Pathways

Effects on

mir21

HIF1a-VEGF

Angiogenesis Ý

let-7 family, miR-22, miR-101

P21, P53 and PTEN

GLUT1-2, IGF-2, BNIP-3

Angiogenesis ß

Metabolic shift ß

miR-17-92

TSP-1 and CTGF

Angiogenesis Ý

miR-497

IGF-1R

Angiogenesis ß

miR-200 family

ZEB1/ZEB2

EMT ß

Mir-185

STIM-1

EMT Ý

Mir-23a-24

FZD5, TMEM92

EMT ß

miR-20

GLUT1-2, IGF-2, BNIP-3

Metabolic shift ß