Group

Control

NTG,

150 mcg/kg

NTG tolerance

NTG tolerance + NADCINÒ

NTG tolerance + MB

NAD, nmol/mg wet tissue

6.75 ± 0.23

6.54 ± 0.37

6.10 ± 0.27*

6.80 ± 0.22#

6.09 ± 0.14*

NADH, nmol/mg wet tissue

6.28 ± 0.39

6.55 ± 0.27

7.05 ± 0.17*

6.25 ± 0.17#

6.98 ± 0.12*

Redox-potential,

NAD/NADH

1.08 ± 0.08

1.0 ± 0.1

0.86 ± 0.06**

1.09 ± 0.09#

0.87 ± 0.07*

NADP, nmol/mg wet tissue

5.70 ± 0.14

5.54 ± 0.17

5.40 ± 0.20

5.80 ± 0.20

5.39 ± 0.24

NADPH, nmol/mg wet tissue

4.67 ± 0.33

4.55 ± 0.19

4.65 ± 0.20

4.65 ± 0.15

4.68 ± 0.22

Redox-potential,

NADP/NADPH

1.22 ± 0.08

1.21 ± 0.10

1.16 ± 0.08

1.24 ± 0.10

1.15 ± 0.08

Total pool of pyridine nucleotide

23.4 ± 0.5

23.2 ± 0.4

23.2 ± 0.4

23.5 ± 0.4

23.1 ± 0.3

ALDH-2, NADH nmol/mg/min

2.25 ± 0.38

1.98 ± 0.27#

0.65 ± 0.07***

2.32 ± 0.23##

1.75 ± 0.24*

Superoxide anion, mmol/mg protein/min

28 ± 4

30 ± 7

45 ± 10

27 ± 5

46 ± 6

ET-1, mg/mg protein

2.34 ± 0.21

2.14 ± 0.23

2.76 ± 0.21

2.03 ± 0.13

2.57 ± 0.18