IR

Non-IR

p value

Media

Medial thickness/total wall thickness

0.76 ± 0.12

0.76 ± 0.15

0.964

Fibrosis proportion

54.4% ± 16.7%

54.9% ± 18.3%

0.943

Smoothelin-positive area/α-SMA-positive area

0.25 ± 0.22

0.37 ± 0.24

0.144

Intima

Intimal thickness/medial thickness

0.34 ± 0.21

0.39 ± 0.43

0.572

S100A4-positive proportion

6.7% ± 7.1%

8.6% ± 7.7%

0.455

EC coverage

Grade A

4 (36.4)

44 (95.7)

Grade B

4 (36.4)

1 (2.2)

Grade C

3 (27.3)

1 (2.2)

p < 0.0001