| % Exposed dose dox excluded from heart | Units doxorubicin retained by Heart* | Equivalent dose dox for cardiac toxicity mgm./M2# | Heart exposure to dox 10 U above Km | Maximum plasma level in U | |
| 1 Bolus q 21 days | 30.40% | 550 | 550 | 3.14 | 79.39 |
| 3 Bolus injections q 21 days | 70.32% | 226.6 | 1290 | 3.02 | 25.07 |
| 9 Bolus injections q 21 days | 79.65% | 152.63 | 1881 | 0 | 9.73 |
| 21 Bolus injections in 21 days q 21 days | 79.88% | 150.9 | 1903 | 0 | 6.32 |
| 4 Day infusion q 21 days | 38.16% | 483.62 | 619 | 2.83 | 21.73 |
| 11 Day infusion q 21 days | 54.91% | 338.82 | 849 | 0 | 8.2 |
| 21 Day infusion q 21 days | 81.39% | 139.92 | 2057 | 0 | 4.29 |