Mean ± SD

n

BL

3M

6M

p value

[eGFR ≥ 60] SCr (mg/dl)

121

0.70 ± 0.15

0.72 ± 0.15

0.72 ± 0.16

0.004^**a

[eGFR < 60] SCr (mg/dl)

70

1.40 ± 0.80

1.43 ± 0.86

1.44 ± 0.98

0.235^a

eGFR ≥ 60 (ml/min/1.73 m²)

121

77.9 ± 13.5

75.9 ± 13.6

75.1 ± 13.7

0.006^**a

eGFR < 60 (ml/min/1.73 m²)

70

43.4 ± 12.6

43.9 ± 13.0

44.8 ± 13.9

0.189^a

[eGFR ≥ 60] BUN (mg/dl)

94

15.8 ± 4.4

15.7 ± 4.1

15.6 ± 3.9

0.947^a

[eGFR < 60] BUN (mg/dl)

56

24.3 ± 9.6

24.0 ± 9.7

23.7 ± 10.4

0.909^a

UA (mg/dl)

80

5.7 ± 1.6

5.6 ± 1.4

5.6 ± 1.3

0.958^a

Alb (g/dl)

42

4.3 ± 0.4

4.3 ± 0.5

4.3 ± 0.5

0.774^b

Hb (g/dl)

75

13.1 ± 1.8

13.1 ± 1.9

13.2 ± 2.0

0.654^b

K (mEq/l)

62

4.4 ± 0.5

4.5 ± 0.5

4.5 ± 0.5

0.137^a

UP

130

0.4 ± 0.8

0.4 ± 0.8

0.3 ± 0.8

0.064^a

HbA1c (%)

526

7.2 ± 0.9

6.9 ± 0.8

6.9 ± 0.8

<0.001^***a

FBG (mg/dl)

183

128.3 ± 34.7

128.3 ± 31.7

127.2 ± 28.9

0.780^a

non HDL-c (mg/dl)

89

135.5 ± 30.9

129.1 ± 29.6

129.2 ± 31.3

0.049^*a

TG (mg/dl)

121

120.9 ± 56.7

111.6 ± 50.3

108.7 ± 48.8

0.028^*a

Systolic blood pressure (mmHg)

651

130.9 ± 16.1

127.1 ± 14.5

127.5 ± 12.7

<0.001^***a

Diastolic blood pressure (mmHg)

651

73.6 ± 9.9

72.0 ± 10.1

72.2 ± 9.2

<0.001^***a

BMI

666

24.4 ± 3.8

24.2 ± 3.8

24.2 ± 3.8

<0.001^***a