Hypotheses	Core Scenario
Description	Continuation of observed epidemiological trends and 2011 cost structure
	2025	2040
Total costs	∈7,934,796,435	∈13,230,271,423
	Core adjusted−H1
	Investments in primary care (annual +5%)
	2025	2040
Total costs	∈7,979,606,895	∈13,459,970,529
cost difference 2011 Core	−∈44,810,460	−∈229,699,106
	Core adjusted−H2
	Investments in pharmaceuticals (annual +2.5%)
	2025	2040
Total costs	∈8,,060,933,449	∈13,786,645,242
cost difference 2011 Core	−∈126,137,015	−∈556,373,819
	Core adjusted−H3a
	Investments in secondary prevention−SMBG (annual +2.5%)
	2025	2040
Total costs	∈7,986,769,133	∈13,466,526,139
cost difference 2011 Core	−∈51,972,699	−∈236,254,715
	Core adjusted−H3b
	Investments in secondary prevention−Patient education (annual +2.5%)
	2025	2040
Total costs	∈7,954,901,428	∈13,321,575,284
cost difference 2011 Core	−∈20,104,993	−∈91,303,861
	Core adjusted−H3c
	Investments in secondary prevention−Patients′ own time (annual +2.5%)
	2025	2040
Total costs	∈8,229,416,849	∈14,562,020,821
cost difference 2011 Core	−∈294,620,415	−∈1,331,749,397