Na+ (μmol/L)

Control

147.29 ± 1.82

147.25 ± 2.50

147.33 ± 3.28

1 mg/Kg bwt

150.29 ± 2.68 (0.95)

154.50 ± 2.90 (0.70)

144.67 ± 2.40 (0.99)

5 mg/Kg bwt

147.25 ± 3.21 (1.00)

149.20 ± 4.75 (1.00)

145.25 ± 4.77 (1.00)

20 mg/Kg bwt

150.25 ± 3.27 (0.60)

149.20 ± 4.61 (1.00)

152.00 ± 5.15 (0.94)

5000 mg/Kg bwt

152.25 ± 2.06 (0.83)

152.50 ± 0.50 (0.94)

152.00 ± 5.00 (0.96)

Ref. range

140 - 151

142 - 151

140 - 150

ANOVA p-value

0.75

0.73

0.66

K+ (μmol/L)

Control

7.58 ± 0.66

7.63 ± 0.93

7.50 ± 1.32

1 mg/Kg bwt

16.18 ± 2.34 (0.30)

15.06 ± 2.05 (0.74)

18.44 ± 7.00 (0.66)

5 mg/Kg bwt

19.11 ± 2.88 (0.08)

19.76 ± 4.09 (0.33)

18.24 ± 4.87 (0.60)

20 mg/Kg bwt

23.02 ± 4.03 (0.01*)

22.75 ± 5.33 (0.13)

23.70 ± 7.51 (0.35)

5000 mg/Kg bwt

10.80 ± 1.55 (0.96)

10.43 ± 1.99 (1.00)

11.26 ± 3.18 (0.99)

Ref. range

3.31 - 4.90

3.82 - 5.55

3.31 - 4.90

ANOVA p-value

0.01*

0.13

0.36

Cl (μmol/L)

Control

102.97 ± 1.61

102.78 ± 1.26

103.23 ± 3.86

1 mg/Kg bwt

104.44 ± 1.21 (0.89)

106.05 ± 1.37 (0.30)

102.30 ± 1.57 (1.00)

5 mg/Kg bwt

102.66 ± 0.83 (1.00)

104.30 ± 0.95 (0.87)

101.03 ± 0.73 (0.94)

20 mg/Kg bwt

104.25 ± 0.90 (0.93)

104.24 ± 1.00 (0.87)

104.27 ± 2.04 (1.00)

5000 mg/Kg bwt

110.25 ± 1.14 (0.006*)

109.8 ± 0.3 (0.02*)

110.70 ± 2.70 (0.29)

Ref. range

100 - 1007

100 - 106

100 - 107

ANOVA p-value

0.005**

0.03*

0.14