Multivariate with no interactions

Statins

Metformin

Prostate volume

ADT

Statins*Metformin

Coefficient

−0.16

[−0.23, −0.09]

−0.34

[−0.48, −0.2]

0.003

[0.002, 0.004]

0.46

[0.39, 0.53]

N/A

p-value

0.03

<0.02

<0.02

<0.001

N/A

Multivariate with interactions

Coefficient

−0.2

[−0.28, −0.12]

−0.64

[−0.84, −0.44]

0.003

[0.002, 0.004]

0.46

[0.39, 0.53]

0.56

[0.27, 0.83]

p-value

<0.01

<0.01

<0.01

<0.001

0.05