| Adverse Drug Event | Burzynski, et al. 2016, Antineoplastons | Packer, et al. 1997 [4] Carboplatin, Vincristine | Prados, et al. 1997 [5] Nitrosourea and multiagent chemotherapy | Gururangan, et al. 2002 [6] Carboplatin | |||
| Grade 3/(%) | Grade 4/(%) | Grade 3 and 4 | Grade 5/(%) | Grade 3/(%) | Grade 4/(%) | Grade 3 and 4 (%) | |
| Hypokalemia | 1 (6%) | 1 (6%) |
|
|
|
|
|
| Hypernatremia | 1 (6%) | 2 (12%) |
|
|
|
|
|
| Somnolence | 1 (6%) |
|
|
|
|
|
|
| Thrombocytopenia |
|
| * |
|
| 3 (7%) | 40 (49%) |
| Neutropenia |
|
|
|
|
| 2 (5%) | 55 (68%) |
| Infection |
|
|
|
|
|
| 12 (15%) |
| Allergic reaction |
|
| * |
|
|
| 4 (5%) |
| Neuropathy |
|
| * |
|
|
|
|
| Nausea |
|
|
|
| 1 (2%) |
|
|
| Septicemia |
|
|
| 1 (1%) |
|
|
|