| Characteristic | FOLFOX | FOLFOX + Dipeptiven | P | 
| All patient rolled | 60 | 60 | |
| Age (years) >50 <50 | 
 22 38 | 
 26 34 | 
 NS | 
| Gender Male Female | 
 33 27 | 
 39 21 | 
 NS | 
| Performances status 0 1 - 2 | 
 21 39 | 
 18 42 | 
 NS | 
| Site of primary tumor Colon Rectum | 
 44 16 | 
 47 13 | 
 NS | 
| Histological differentiation Grade I-II Grade II-IV | 
 32 28 | 
 26 34 | 
 NS | 
| Site of metastases Liver only Liver and others Others | 
 27 25 8 | 
 24 28 8 | 
 NS | 
| Surgical procedures Radical surgery (n = 20) Rt hemicolectomy Lt hemicolectomy Extended Rt hemicolectomy Extended Lt hemicolectomy Low ant resect. of Dixon 
 Palliative surgery(n = 10) Hartman’s operation Colostomy Bypass Ileostomy | 
 11 4 2 2 1 2 
 5 1 2 1 1 | 
 9 3 2 2 1 1 
 5 2 1 0 2 | 
 NS 
 
 
 
 
 NS | 
| Serum CEA level >5 <5 | 
 32 28 | 
 37 23 | 
 NS |