Variable | baseline | The 1st course | The 2nd course | The 3rd course | P value | CI | ||||||
Acute asthma attack in past year―no. (%) | ||||||||||||
| 91 (29.4) | 81 (26.1) | 67 (21.6) | 71 (22.9) | 0.000### | 21.563 | ||||||
Days for asthma-related symptoms in last 12 months―(means ± SD) | ||||||||||||
| 106.49 ± 142.83 | 66.22 ± 110.68 | 42.49 ± 81.51 | 42.31 ± 88.82 | 0.000### |
| ||||||
Pulmonary function test | ||||||||||||
| 1.85 ± 0.94 | 1.73 ± 0.67 | 1.92 ± 1.51 | 1.80 ± 0.98 | 0.233 |
| ||||||
| 81.68 ± 19.06 | 82.76 ± 14.89 | 83.37 ± 14.60 | 79.50 ± 19.17 | 0.221 |
| ||||||
Asthma-related health care in last 12 months―no. (%) | ||||||||||||
≥1 Admit to A & E | 20 (22) | 10 (11) | 10 (11) | 6 (6.6) | 0.014# | 10.65 | ||||||
≥1 Hospitalization | 14 (15.4) | 7 (7.7) | 4 (4.4) | 3 (3.3) | 0.010# | 11.452 | ||||||
≥1 Outpatient visit | 74 (81.3) | 44 (48.4) | 49 (54.4) | 50 (55.6) | 0.000### | 24.264 | ||||||
≥1 Prescription | 79 (86.8) | 76 (83.5) | 58 (63.7) | 62 (68.1) | 0.000### | 18.926 | ||||||
≥1 By own medication | 12 (13.2) | 12 (13.2) | 6 (6.6) | 7 (7.7) | .0296# | 3.700 | ||||||
≥1Not to be proceed | 9 (9.9) | 10 (11) | 10 (11) | 8 (8.8) | .0331# | 0.954 | ||||||
The frequency of bronchodilator during asthma attack―no. (%) | ||||||||||||
More than twice per day | 24 (27.3) | 15 (17) | 12 (13.6) | 37 (42) | 63.257 |
| ||||||
Once to twice per day | 33 (39.3) | 28 (33.3) | 13 (15.5) | 10 (11.9) | ||||||||
Twice to three times per week | 9 (47.4) | 3 (15.8) | 6 (31.6) | 1 (5.3) | ||||||||
Less than once per week | 15 (26.3) | 13 (22.8) | 19 (33.3) | 10 (17.5) | ||||||||
Never | 9 (8.9) | 29 (28.7) | 28 (37.6) | 25 (24.8) | ||||||||