Author

Region

Year

Platform

Number of Tissues

Altered miRNAs

Criteria

Up-Regulated miRNAs in HCC

Down-Regulated miRNAs in HCC

Qi

China

2014

GPL9052 Illumina

31 (7/24)

4

p < 0.05

4

Sand

Germany

2013

Agilent Microarray

42 (21/21)

49

p < 0.05

21

28

Xu

UK

2012

Illumina microarray

32 (21/21)

24

p < 0.05

10

14

Poliseno

USA

2012

miRCURY LNA 11.0 array (Exiqon)

91 (82/9)

27

p < 0.05

27

Yang

China

2011

LuxScan 3.0

8 (4/4)

7

?

5

2

Caramta

USA

2010

Agilent Microarray

19 (16/3)

54

p < 0.01

48

6

Segura

USA

2010

Agilent Microarray

118 (59/59)

12

p < 0.05

12

Chen

Canada

2010

Agilent Microarray

16 (8/8)

31

p < 0.05

13

18

Philippidou

Luxemburg

2010

uParaflo microarray

40 (20/20)

45

p < 0.05

25

20

Schultz

Germany

2008

ABI 7700 systerm

20| (10/10)

72

p < 0.05

6

66