| Primary Causes | ||
| Genetic causes | ||
| Monogenic disorders Melanocortin-4 receptor mutation Leptin deficiency Proopiomelanocortin deficiency | Syndromes Prader-Willi Bardet-Biedl Cohen Alström Froehlich | |
| Secondary Causes | ||
| Neurological Brain injury Brain tumour Consequences of cranial irradiation Hypothalamic obesity | Drug-Induced Psychiatric medications (tricyclic antidepressants, antipsychotics, anticonvulsants) Anti-diabetes drugs (sulfonylureas, glitazones, thiazolidinediones, insulin) Other (glucocorticoids, oral contraceptives, beta-blockers) | |
| Endocrine Hypothyroidism Cushing syndrome Growth hormone deficiency Pseudo-hypoparathyroidism Polycystic ovary syndrome | ||
| Socioeconomic Urban environment Work and school exercise opportunity | ||
| Psychological Eating disorders Depression associated with eating disorders Sleep disorders | ||