Treatments

Dose (mg/kg)

Number of line crossing (s)

Duration of ambulation

KET

10

129.0 ± 4.77

96.40 ± 6.78

DOX

25

125.0 ± 3.53

94.20 ± 8.59

DOX

50

123.6 ± 2.08

92.80 ± 3.85

DOX

100

105.6 ± 2.59

88.6 ± 10.80

DOX

200

90.40 ± 4.14*

184.2 ± 7.98*

RIS

0.5

32.20 ± 4.99*

223.6 ± 9.33*