Sample

Macrophage activity

Nitrite (μM)

Phagocytosis (%)

TNF-α (pg/mL)

IL-1β (pg/mL)

IL-6 (pg/mL)

CT-26 only

8.29 ± 0.54^d

41.19 ± 5.27^b

1528.4 ± 132.5^c

95.7 ± 10.7c

126.8 ± 10.5^c

αPD-1 only

11.73 ± 1.52^c

45.58 ± 5.11^b

1944.5 ± 152.5^b

125.9 ± 16.7^b

162.8 ± 19.9^b

40 mg/kg BRB-F

31.81 ± 2.79^b

80.54 ± 7.29^a

3529.8 ± 407.9^a

257.1 ± 18.9^a

385.9 ± 42.5^a

αPD-1 + 40 mg/kg BRB-F

35.29 ± 2.69^a

83.76 ± 10.89^a

3382.5 ± 284.3^a

238.6 ± 30.8^a

401.7 ± 34.8^a