Cell type | Radiation type and dose | Observed bystander response | Reference |
Epithelial (IR), fibroblasts (By) | g-rays, 1 - 100 cGy | clonogenic survival decreased | [10] |
Chinese hamster fibroblasts | α-particles, 0.31 & 0.49 mGy | SCE increased | [11] |
Human fibroblasts | α-particles, 1.5 - 8.4 cGy | SCE increased | [12] |
Human fibroblasts | α-particles, X-rays (0.1 Gy) | micronuclei and apoptosis increased | [13] |
Human malignant melanoma | g-rays, 5 Gy | micronuclei, apoptosis, DNA ssb, SOD, MDA all increased | [14] |
Human dermal fibroblasts vs human malignant melanoma | X-rays (6 MV), 2 & 4 Gy | micronuclei and apoptosis decreased in irradiated cells | [8] |
Human malignant melanoma | X-rays (6MV), 3 - 20 Gy, spatially modulated field | clonogenic survival decreased in low dose regions, increased in high dose regions | [15] |
Human embryonic stem cells and bone marrow stem cells | X-rays, 0.2, 2.0, 10 Gy | DNA damage and apoptosis unchanged | [17] |
Human fibrosarcoma stem-like cells and non-stem-like cells | photons (3.7 MeV), 2.2 Gy | DNA dsb increased more in non-stem-like cells | [18] |
Human normal fibroblasts, human colon carcinoma | X-rays, γ-rays, energetic electrons, 10 - 100 cGy | clonogenic survival, DNA dsb and micronuclei, all unchanged | [19] |
Human colorectal carcinoma | X-rays, 2 - 8 Gy | survival decreased, apoptosis micronuclei, and senescence increased | [20] |
Murine hemopoietic stem cells | α-particles, 0.25 - 1 Gy | clonogenic survival decreased, chromosomal aberrations increased | [26] |
Human keratinocytes | g-rays, 0.1 - 0.5 Gy | clonogenic survival decreased | [35] |
Human colorectal carcinoma | X-rays (6 MV), 2 - 8 Gy | clonogenic survival decreased, senescence increase | [37] |
Human lung fibroblasts and lung adenocarcinoma | 22 MeV electrons, 6 MV photons, 5 Gy | micronuclei and apoptosis increased | [44] |
Human malignant melanoma | X-rays (6 MV), 3 × 0.5 Gy vs 1.5 Gy; 3 × 2 Gy vs 6 Gy | higher increase of micronuclei and apoptosis in fractionated RT | [38] |
Human keratinocytes | 5 mGy-5 Gy, g-rays given as single or split doses | clonogenic survival declined deeper after split dose | [39] |
Human lung fibroblasts and lung carcinoma | 1, 2, 4 Gy given as single or split doses | micronuclei and apoptosis inreased comparably in both schemes | [40] |
Normal human lung fibroblasts | g-rays, radioadaptive 1cGy, challange 2 - 4 Gy | clonogenic survival increased | [5] |
Murine fibroblasts vs murine lung carcinoma | X-rays (6 MV), 2 & 4 Gy) | apoptosis and micronuclei decreased | [7] |
Human primary fibroblasts vs human cervical carcinoma | α-particles, 20 & 40 cGy | apoptosis and micronuclei decreased | [6] |
Human normal fibroblasts vs human malignant melanoma | X-rays (6 MV), 2 & 4 Gy | apoptosis and micronuclei decreased | [20] |
Umbilical stromal cells | g-rays, 2 - 8 Gy | clonogenic survival and apoptosis unchaneged | [16] |
Human malignant melanoma | g-rays, 2 - 8 Gy | clonogenic survival decreased, apoptosis increased | [16] |