SOC | PT | DHEC (n = 56) | PRAM (n = 60) | |||
|
| Week 1 | Week 10 | Week 16 | Week 10 | Week 16 |
Gastrointestinal disorders | Nausea | 3 | 8 | 3 | 6 | 2 |
| Vomiting |
| 2 |
|
|
|
| Dry mouth |
| 2 |
|
|
|
| Salivation |
| 1 |
|
|
|
| Diarrhoea |
|
|
| 1 |
|
| Gastritis |
|
| 1 | 1 |
|
| Constipation |
| 1 |
| 1 |
|
| Heartburn |
| 2 |
|
|
|
| Abdominal pain upper |
| 1 |
|
|
|
Metabolism and nutrition disorders | Decreased appetite | 1 | 1 |
|
|
|
Musculoskeletal and connective tissue disorders | Rigidity |
| 3 |
| 1 |
|
| Pain in arm |
| 1 |
|
|
|
Nervous system disorders | Lower extremities weakness | 1 |
|
|
|
|
| Bradykinesia |
|
|
|
| 1 |
| Dyskinesia |
| 3 |
| 3 | 2 |
| Balance difficulty | 1 |
|
|
|
|
| Festinating gait |
|
|
| 1 |
|
| Headache |
| 4 | 2 |
|
|
| Drowsiness |
| 2 |
| 1 | 1 |
| Insomnia |
|
| 1 |
|
|
| Vivid dreams |
|
|
|
| 1 |
| Confusion |
|
|
| 1 |
|
| Thirst |
|
|
| 1 |
|
| Asthenia |
|
|
| 1 |
|
| Flashing vision | 1 |
|
|
|
|
| Movement disorder |
| 1 |
|
|
|
| Parkinsonism aggravated |
|
|
| 1 |
|
| Dopamine dysregulation syndrome |
| 1 |
|
|
|
General disorders and administration site conditions | Fatigue |
| 1 |
|
|
|
| Lack of efficacy |
|
|
| 1 |
|
| Malaise | 1 |
|
|
|
|
Respiratory, thoracic and mediastinal disorders | Dyspnoea |
| 1 |
|
|
|
Skin and subcutaneous tissue disorders | Livedo reticularis |
|
|
|
| 1 |
| Skin rash |
|
|
| 1 |
|