| S. No. | First Author | Year of Study | Study Design | Region | Diagnostic Method | Median Age, Range (in Years) | Total No. of Subjects, n | NSCLC, n (%) | ADC Cases in NSCLC, n (%) | EGFR Positive Cases in ADC, n (%) |
| 1 | Samdariya et al. [49] | 2016 | Retrospective study | Jodhpur, India | NR | 13 - 80 | 133 | 122 (92) | 37 (30) | 20 (54) |
| 2 | Rana et al. [50] | 2017 | Clinical and epidemiological study | Pune, India | PCR and gene sequencing | 57.5 (25 - 86) | 152 | 152 (100) | 135 (88.8) | 48 (35.5) |
| 3 | Bal et al. [28] | 2016 | Retrospective study | Chandigarh, India | RT-PCR | 61.8 (mean) | 240 | 240 (100) | 240 (100) | 37 (15.4) |
| 4 | Verma et al. [21] | 2017 | Retrospective and prospective study | Lucknow, India | IHC | 55.3 (Mean) | 69 | 69 (100) | 18 (26.1) | 14 (77.8) |
| 5 | Doval et al. [30] | 2015 | Retrospective study | Indian multi-centric (6 centres) | FISH | 58 | 500 | 500 (100) | 500 (100) | 164 (32.8) |
| 6 | Doval et al. [51] | 2017 | Retrospective study | New Delhi, India | PCR | 60 (24 - 90) | 401 | 322 (80.3) | 196 (60.9) | 33* (22.8) |
| 7 | Bhatt et al. [52] | 2013 | Retrospective study | Vellore, India | PCR | 55 | 154 | 106 (55) | 76 (72) | 42 (55.2) |
| 8 | Shankar et al. [53] | 2014 | Retrospective study | Chennai, India | IHC | <40 to >80 | 90 | 84 (93) | 46 (55) | 41 (89) |
| 9 | Singh et al. [20] | 2017 | Retrospective study | New Delhi, India | RT-PCR | 62 | 421 | 388 (92.2) | 223 (57.5) | 24** (20) |
| 10 | Ashutosh et al. [36] | 2016 | Cross-sectional | New Delhi, India | PCR | 56.2 (Mean) | 102 | 102 (100) | 102 (100) | 21 (20.6) |
| 11 | Sahoo et al. [54] | 2011 | Retrospective study | Bangalore, India | RT-PCR | 59 | 220 | 220 (100) | 176 (80) | 114 (64.7) |
| 12 | Bala et al. [29] | 2016 | Retrospective study | Hyderabad, India | RT-PCR | 58 | 353 | 353 (100) | 250 (70.8) | 47# (35) |
| 13 | Jain et al. [25] | 2017 | Retrospective study | New Delhi, India | Sanger sequencing and RT-PCR | 58 | 116 | 116 (100) | 84 (72.4) | 17 (20.2) |
| 14 | Sharma et al. [19] | 2018 | Retrospective study | Chandigarh, India | PCR | 61 - 80 | 61 | 61 (100) | 48 (79) | 19 (39.6) |
| 15 | Udupa et al. [35] | 2015 | Cross-sectional | Chennai, India | RT-PCR | 55 | 85 | 85 (100) | 85 (100) | 34 (40) |
| 16 | Chatterjee et al. [17] | 2016 | Cross-sectional | Kolkata, India | PCR followed by bidirectional Sanger’s sequencing | 58 | 224 | 224 (100) | 214 (96) | 68 (31.7) |
| 17 | Vaid et al. [27] | 2013 | Retrospective study | North India | PCR | 61.5 (27 - 87) | 105 | 105 (100) | 80 (76.2) | 22 (27.5) |
| 18 | Chatterjee et al. [16] | 2017 | Retrospective study | Kolkata, India | RT-PCR | 56 (42 - 72) | 108 | 106 (98) | 106 (100) | 35 (33) |
| 19 | Ansari et al. [55] | 2017 | Case control study | North India | RT-PCR | 54.5 ± 11.5 (Mean ± SD) | 111 | 111 (100) | 61 (55) | 14 (22.9) |
| 20 | Kota et al. [56] | 2015 | Retrospective study | Hyderabad, India | RT-PCR | 56 (30 - 80) | 147 | 111 (75.5) | 95 (85.6) | 34 (35.8) |
| 21 | Singh et al. [34] | 2018 | Retrospective study | North India | RT-PCR | 58 | 125 | 125 (100) | 125 (100) | 31 (24.8) |
| 22 | Gupta et al. [57] | 2019 | Prospective study | Hyderabad, India | PCR | 58.2 | 64 | 64 (100) | 51 (80) | 23 (45.1) |
| 23 | Noronha et al. [33] | 2017 | Retrospective study | Mumbai, India | RT-PCR | 56 (49 - 62) | 580 | 580 (100) | 580 (100) | 227 (39.1) |
| 24 | Kasana et al. [32] | 2018 | Cross-sectional | Jammu and Kashmir, India | PCR | 56.9 (Mean) | 57 | 57 (100) | 57 (100) | 20 (35.1) |
| 25 | Choughule et al. [18] | 2013 | Retrospective study | Mumbai, India | PCR | NA | 1018 | 1018 (100) | 255 (25) | 255 (100) |
| 26 | Bharadwaj et al. [58] | 2016 | Retrospective study | New Delhi, India | IHC | 62.7 (42 - 79) (Mean) | 60 | 60 | 20 (33.3) | 18 (90) |
| 27 | Poonamalle et al. [23] | 2013 | Retrospective study | India | IHC | > 50 | 35 | 35 (100) | 26 (74.3) | 21 (80.7) |
| 28 | Dutt et al. [24] | 2014 | Cohort study | India | PCR | 57.9 (25 - 90) | 3351 | 3079 (92) | 3079 (100) | 748## (28.2) |
| 29 | Prabhash et al. [42] | 2017 | Retrospective study | Indian multicentric | RT-PCR | 57 | 301 | 252 (84) | 213 (84.5) | 59 (27.7) |
| 30 | Doval et al. [31] | 2013 | Retrospective study | New Delhi, India | PCR | 60 | 166 | 166 (100) | 166 (100) | 43 (25.9) |
| 31 | Dang et al. [59] | 2013 | Retrospective study | India | IHC | NA | 149 | 149 (100) | 63 (42) | 38*# (90) |
| 32 | Chougule et al. [41] | 2013 | Retrospective study | Mumbai, India | RT-PCR | Males 57, females 54 | 907 | 907 (100) | 780 (86) | 210 (26.9) |
| 33 | Noronha et al. [26] | 2013 | Retrospective study | Mumbai, India | RT-PCR | 55 | NA | 111 | 107 (96.4) | 39 (36.4) |
| 34 | Kumari et al. [60] | 2019 | Cross-sectional | Lucknow, India | RT-PCR | 60 (26 - 87) | 530 | 226 (90) | 169 (74.8) | 79 (46.7) |