Drug/Dose

(mg/kg)

Analgesia TFLD or Mean Increase in Latency after Drug Administration ± S.E.M

Pre-drug

30 min

60 min

90 min

120 min

150 min

180 min

210 min

Control

1.5 ± 0.1

0.12 ± 0.07

0.12 ± 0.2

0.08 ± 0.3

0.14 ± 0.14

0.1 ± 0.14

0.1 ± 0.14

0.25 ± 0.14

T. chebula 300

1.6 ± 0.4

^*2.7 ± 0.4

^*2.8 ± 0.4

^*2.9 ± 0.2

^*2.9 ± 0.2

^*2.9 ± 0.6

^**3.1 ± 0.2

^**3.1 ± 0.1

Aspirin 300

1.6 ± 0.1

2.2 ± 0.1

2.4 ± 0.1

2.1 ± 0.1

2.5 ± 0.2

^*2.6 ± 0.2

^*2.9 ± 0.1

^*2.7 ± 0.2

T. chebula 500

1.3 ± 0.1

^**3.8 ± 0.4

^**4.1 ± 0.4

^**4.2 ± 0.2

^**4.4 ± 0.1

^**4.5 ± 0.6

^**4.4 ± 0.2

^**4.3 ± 0.1

Aspirin 500

1.4 ± 0.1

^*3.0 ± 0.1

^**3.1 ± 0.3

^**3.2 ± 0.2

^**3.4 ± 0.2

^**3.7 ± 0.2

^**3.4 ± 0.1

^**3.3 ± 0.2

T. chebula 1000

1.6 ± 0.1

^**5.6 ± 0.4

^**5.6 ± 0.4

^**5.8 ± 0.2

^**5.9 ± 0.1

^**6.1 ± 0.6

^**6.1 ± 0.2

^**5.8 ± 0.1

Aspirin 1000

1.5 ± 0.1

^**4.1 ± 0.4

^**4.6 ± 0.3

^**4.8 ± 0.2

^**5.0 ± 0.2

^**5.5 ± 0.2

^**5.9 ± 0.1

^**5.1 ± 0.2