Element

Control subjects (n = 18)

OA patients (n = 43)

P value

Serum Zinc (μg/ml)

2.1 ± 0.54

0.73 ± 0.17

<0.0001

Serum Copper (μg/ml)

1.33 ± 0.35

3.05 ± 0.81

<0.0001

Serum Selenium (μg/ml)

0.16 ± 0.03

0.054 ± 0.002

<0.0001

Serum Manganese (μg/ml)

0.64 ± 0.06

0.47 ± 0.11

<0.001

Serum Magnesium (μg/ml)

18.9 ± 2.3

18.01 ± 1.7

0.16

Copper/Zinc ratio

0.69 ± 0.29

4.8 ± 3.1

<0.0001