t [min] = 15

t [min] = 30

MβCD [μM]

0 β-A

2.5 β-A

0 β-A

2.5 β-A

0

111.5 ± 0.8

150 ± 30

118.2 ± 1.5

150 ± 30

0.5

110.5 ± 2.4

195 ± 14

114.8 ± 2.0

206 ± 9

1

112 ± 4

174 ± 16

115 ± 6

175 ± 14

1.5

111.4 ± 1.0

182 ± 4

116.5 ± 1.0

192 ± 7

2

111.7 ± 1.0

176 ± 22

117.7 ± 2.2

182 ± 26

2.5

119 ± 8

168 ± 15

122 ± 8

178 ± 20

t [min] = 45

t [min] = 60

MβCD [μM]

0 β-A

2.5 β-A

0 β-A

2.5 β-A

0

121.8 ± 1.1

160 ± 30

129.1 ± 1.6

170 ± 30

0.5

119.9 ± 2.4

220 ± 9

125.0 ± 2.9

234 ± 12

1

123 ± 6

182 ± 16

128 ± 8

194 ± 20

1.5

123.1 ± 0.7

199 ± 9

129.3 ± 1.4

209 ± 10

2

122.3 ± 2.5

183 ± 23

129 ± 4

200 ± 30

2.5

131 ± 8

192 ± 26

138 ± 9

200 ± 30

t [min] = 90

t [min] = 120

MβCD[μM]

0 β-A

2.5 β-A

0 β-A

2.5 β-A

0

121.1 ± 1.8

150 ± 30

112.5 ± 2.5

141 ± 28

0.5

120.4 ± 2.4

217 ± 10

108.1 ± 0.9

203 ± 9

1

122 ± 7

187 ± 16

112 ± 5

168 ± 16

1.5

124 ± 4

203 ± 7

112 ± 4

185 ± 6

2

122 ± 4

217 ± 23

108 ± 4

167 ± 18

2.5

131 ± 8

196 ± 20

108 ± 5

175 ± 23

t [min] = 150

t [min] = 180

MβCD [μM]

0 β-A

2.5 β-A

0 β-A

2.5 β-A

0

111.1 ± 2.7

170 ± 30

108 ± 3

143 ± 23

0.5

105.5 ± 1.4

193 ± 8

101.8 ± 0.8

183 ± 7

1

108 ± 5

162 ± 15

103.5 ± 3.2

158 ± 12

1.5

109 ± 3

177 ± 7

104 ± 4

167 ± 8

2

104 ± 3

165 ± 24

99 ± 4

155 ± 19

2.5

107 ± 8

168 ± 22

101 ± 6

158 ± 19

t [min] = 210

t [min] = 240

MβCD [μM]

0 β-A

2.5 β-A

0 β-A

2.5 β-A

0

107 ± 4

140 ± 23

116 ± 4

155 ± 26

0.5

99.5 ± 1.5

178 ± 8

107.9 ± 2.0

197 ± 8