| Reactions | ΔEr (kcal/mol) | ΔHr (kcal/mol) | ΔGr (kcal/mol) | ΔCr (kcal/mol-Kelvin) | ΔSr (kcal/mol-Kelvin) |
| NAPA-A + H2O → [NAPA-A(H2O)1] | −9.27 | −9.87 | −0.52 | 0.0030 | −0.0313 |
| [NAPA-A(H2O)1] + H2O → [NAPA-A(H2O)2] | −12.77 | −13.36 | −2.86 | 0.0025 | −0.0352 |
| [NAPA-A(H2O)2] + H2O → [NAPA-A(H2O)3] | −8.00 | −8.60 | 0.08 | 0.0034 | −0.0291 |
| [NAPA-A(H2O)3] + H2O → [NAPA-A(H2O)4] | −5.68 | −6.27 | 1.86 | 0.0041 | −0.0272 |