Derivatives | IC50a | Db | STc | IoRd | logPe | MRf | Jg | J_MSDh |
D1 | 19.54 | 1.583 | 85.4 | 1.744 | 3.064 | 69.13 | 1.899 | 4.05 |
D2 | 20 | 1.597 | 86.1 | 1.706 | 1.804 | 101.44 | 1.486 | 6.236 |
D3 | 20 | 1.52 | 76.7 | 1.648 | 2.265 | 119.45 | 1.522 | 7.001 |
D4 | 9.27 | 1.52 | 76.7 | 1.648 | 2.486 | 119.45 | 1.497 | 7.161 |
D5 | 3.16 | 1.52 | 76.7 | 1.648 | 2.401 | 119.45 | 1.479 | 7.27 |
D6 | 2.25 | 1.57 | 85.3 | 1.68 | 2.254 | 109.87 | 1.45 | 6.96 |
D7 | 2.78 | 1.32 | 62.4 | 1.606 | 4.703 | 137.75 | 1.49 | 7.519 |
D8 | 2.6 | 1.49 | 71.4 | 1.614 | 1.99 | 170.81 | 1.383 | 9.076 |
D9 | 3.63 | 1.39 | 61.5 | 1.599 | 2.12 | 129.13 | 1.556 | 7.167 |