Derivatives

IC50a

Db

STc

IoRd

logPe

MRf

Jg

J_MSDh

D1

19.54

1.583

85.4

1.744

3.064

69.13

1.899

4.05

D2

20

1.597

86.1

1.706

1.804

101.44

1.486

6.236

D3

20

1.52

76.7

1.648

2.265

119.45

1.522

7.001

D4

9.27

1.52

76.7

1.648

2.486

119.45

1.497

7.161

D5

3.16

1.52

76.7

1.648

2.401

119.45

1.479

7.27

D6

2.25

1.57

85.3

1.68

2.254

109.87

1.45

6.96

D7

2.78

1.32

62.4

1.606

4.703

137.75

1.49

7.519

D8

2.6

1.49

71.4

1.614

1.99

170.81

1.383

9.076

D9

3.63

1.39

61.5

1.599

2.12

129.13

1.556

7.167