Groups

Number

2−∆∆Ct (Mean ± SEM)

ANOVA p-value

Duration of Disease

<5 years

5 - 10 years

>10 years

14

26

11

2.722 ± 0.889

8.129 ± 3.421

4.020 ± 2.168

NS

Disease Activity Score (DAS-28)

Low

Medium

High

2

29

20

1.927 ± 0.920

7.541 ± 3.076

3.557 ± 1.335

NS

Rheumatoid Factors

Positive

Negative

27

24

3.851 ± 1.085

7.905 ± 3.697

NS

C-reactive Protein

Positive

Negative

33

18

6.401 ± 2.735

4.581 ± 1.449

NS

ACCP antibodies

Weak positive

Moderate positive

Strong positive

24

8

19

4.061 ± 1.366

1.566 ± 1.104

9.668 ± 3.518

0.043