| Efficacy | Virological | Immunological | Clinical | Thermodynamics | ||
| Marker | Viral load | CD4 cells count | Clinical stage | Absolute combined Hamaker coefficients | ||
| Time | 24 weeks | 48 weeks | 24 - 48 weeks | By 12 weeks | 24 weeks | 48 weeks |
| Suggested range | <400 copies/ml of HIV | <50 copies/ml of HIV | Increase from baseline by at least 50 - 100 cells/mm3 | Stage 1 or 2 | Negative A132abs for HIV +ve blood and positive A131abs for HIV −ve blood | Increased negative A132abs for HIV +ve blood and decreased positive A131abs for HIV −ve blood |
| Response | Reduced viral loads to clinically undetectable levels | Increased CD4 cell count to at least 350 cells/mm3 | Symptoms of HIV infection abate or subside | Net repulsive van der Waals forces between HIV and drug treated lymphocytes, resulting in increase in surface energy of HIV +ve blood | ||