G1 < 2 H/Y

G2 ≥ 2 H/Y

P

Age (years)

67.6

66.9

0.31

Gender (Male,%)

96.7

97.1

0.79

BMI (kg/m²)

24.04

23.83

0.61

Comorbidities ≥ 1 (%)

87

85.3

0.45

Cardiovascular comorbidities (%)

38.9

44.1

0.11

Diabetes

14.4

19.6

0.032

Smoking status:

Current or ex-smokers (%)

96.1

98.3

0.26

mMRC ≥ 2 (%)

56

87

<10-3

FVC (L)

1.91

1.62

<10-3

FEV1 post β2 (L)

1.24

0.97

<10-3

FEV1/FVC post β2 (%)

58.4

54.5

<10-3

Mean FEV1 decline (ml/year)

56

65

0.035

PaO₂ (mmHg)

70.2

63.5

<10-3

PaCO₂ (mmHg)

40.4

43.2

<10-3

N of AE/year

2.1

4.7

<10-3

AE due to Pyocyanic (%)

4

15.4

<10-3

Chronic respiratory failure (%)

48

75

<10-3