All (n = 72)

ASSD (n = 36)

IMNM (n = 8)

DM (n = 28)

Control (n = 67)

P value*

Demographics

Age (years)

48.1 ± 12.8

47.2 ± 14.9

53.6 ± 12.2

47.7 ± 11.7

46.2 ± 15.4

0.458

Female (%)

54 (75.0)

25 (69.4)

7 (87.5)

22 (78.6)

58 (86.6)

0.092

BMI (kg/m2)

27.2 ± 6.4

27.9 ± 7.1

23.5 ± 6.1

27.3 ± 5.4

25.2 ± 3.7

0.197

Disease status

Physician’ VAS (0 - 10)

0.0 (0.0 - 0.0)

0.0 (0.0 - 0.0)

0.0 (0.0 - 0.0)

0.0 (0.0 - 0.0)

-

-

Patient’s VAS (0 - 10)

4.2 (0.0 - 6.5)

3.0 (0.0 - 7.0)

5.0 (2.5 - 5.7)

5.0 (2.0 - 6.7)

-

-

HAQ (0.0 - 3.0)

0.4 (0.0 - 1.2)

0.3 (0.0 - 1.0)

0.4 (0.0 - 1.8)

0.7 (0.3 - 1.6)

-

-

MMT-8 (0 - 80)

80 (80 - 80)

80 (80 - 80)

80 (80 - 80)

80 (80 - 80)

-

-

Creatine phosphokinase (U/L)

109 (67 - 201)

116 (71 - 193)

300 (54 - 594)

94 (65 - 194)

-

-

Treatment

Prednisone (%)

21 (29.2)

7 (19.4)

2 (25.0)

12 (42.9)

-

-

Prednisone (mg/day)

0.0 (0.0 - 5.0)

0.0 (0.0 - 5.0)

0.0 (0.0 - 15.0)

0.0 (0.0 - 10.0)

-

-

Methotrexate (%)

6 (8.3)

2 (5.6)

1 (12.5)

3 (10.7)

-

-

Azathioprine (%)

14 (19.4)

5 (13.5)

1 (12.5)

8 (28.6)

-

-

Mycophenolate mofetil (%)

14 (19.4)

7 (19.4)

3 (37.5)

4 (14.3)

-

-

Other drugs

Anti-hypertensive (%)

24 (33.3)

9 (25.0)

1 (12.5)

14 (50.0)

-

-

Anti-depressants (%)

4 (5.6)

1 (2.8)

0

3 (10.7)

-

-

Pain-relievers (%)

13 (18.1)

4 (11.1)

1 (12.5)

8 (28.6)

-

-

Lipid-lowering drugs (%)

5 (6.9)

3 (10.7)

0

2 (5.6)

-

-

Comorbidities

Arterial hypertension (%)

24 (33.3)

9 (25.0)

1 (12.5)

14 (50.0)

-

-

Dyslipidemia (%)

15 (20.8)

8 (22.2)

2 (25.0)

5 (17.9)

-

-

Hypothyroidism (%)

5 (6.9)

3 (8.3)

0

2 (7.1)

-

-

Diabetes mellitus (%)

14 (19.4)

4 (11.1)

0

10 (35.7)

-

-

Depression (%)

1 (1.4)

0

0

1 (3.6)

-

-

Fibromyalgia (%)

6 (8.3)

3 (8.3)

0

3 (10.7)

-

-

Pain perception (VAS)

Light (0.0 - 3.0)

26 (36.1)

18 (50.0)

2 (25.0)

6 (21.4)

34 (50.7)

Moderate (4.0 - 8.0)

29 (40.3)

10 (27.8)

5 (62.5)

14 (50.0)

26 (38.8)

0.045

Intense (8.0 - 10)

17 (23.1)

8 (22.2)

1 (12.5)

8 (28.6)

7 (10.4)

Fatigue perception (VAS)

Mild (0.0 - 3.0)

24 (33.3)

16 (44.4)

2 (25.0)

8 (21.4)

20 (29.9)

Moderate (4.0 - 8.0)

27 (37.5)

10 (27.8)

3 (37.5)

14 (50.0)

30 (44.8)

0.702

Intense (8.0 - 10)

21 (29.2)

10 (27.8)

3 (37.5)

8 (28.6)

17 (25.4)

Fatigue severity

FSS (0.0 - 7.0)

4.0 ± 2.1

3.4 ± 1.8

3.5 ± 0.4

4.9 ± 0.7

3.6 ± 1.5

0.726

Physical activity levels

Low

52 (72.2)

26 (72.2)

7 (87.5)

19 (67.9)

37 (56.1)

Moderate

16 (22.2)

8 (22.2)

1 (12.5)

7 (25.0)

14 (21.2)

0.053

High

4 (5.6)

2 (5.6)

0

2 (7.1)

15 (22.7)