MTX + HCQ

Time when both medications were discontinued

Discontinued medication

Continued medication

p

1) month prior N (%)

59

(100)

526

(100)

1^b

Infections No

57

(97)

503

(96)

Yes

2

(3)

23

(4)

2) months prior N (%)

30

(100)

615

(100)

0.65^b

Infections No

28

(93)

586

(95)

Yes

2

(7)

29

(5)

3) months prior N (%)

14

(100)

656

(100)

0.47^b

Infections No

13

(93)

627

(96)

Yes

1

(7)

29

(4)