Patient no.

Age^$/Se^x

ISS^*/DS¶

Subtype

Best response before the initial increased bortezomib therapy dose

Disease status at treatment

Preceding bortozomib based treatment more than 3 times per month (months)

Preceding bortozomib based treatment (months)

Treatment

Treatment duration (months)

1

76/F

I/IIIB

IgG

SD

SD

0

32

BMP Bor 1.6 mg/m² on Day 1, Mel 8 mg/body on Days 1-4, Dex 20 mg/body on Days 1, 2, Psl 50 mg/body on Days 1-4.

5

2

59/F

I/IA

BJP

ND

ND

10

23

BMP Bor 1.6 mg/m² on Day 1, Mel 8 mg/body on Days 1-4, Dex 20 mg/body on Days 1-2, and Psl 20 mg/body on Days 1-4

5

3

81/F

II/IIIA

IgG

PR

PR

0

15

BD Bor 1.6 mg/m² on Day 1 and Dex 20 mg/body on Days 1-2

2

4

69/F

II/IA

IgG

PR

PR

0

8

BD Bor 1.6 mg/m² on Day 1 and Dex 20 mg/body on Days 1-2

13#

5

65/M

II/IIIA

IgG

PR

PR

3

52

BD Bor 1.6 mg/m² on Day 1 and Dex 20 mg/body on Days 1-2

17#

6

67/M

I/IIIB

IgG

SD

SD

2

30

BD Bor 1.6 mg/m² on Day 1 and Dex 20 mg/body on Days 1-2

3

7

68/M

II/IIB

IgG

PR

PR

4

45

BD Bor 1.6 mg/m² on Day 1 and Dex 20 mg/body on Days 1-2

10

8

76/M

I/IIA

IgG

PR

PD

10

17

BD Bor 1.6 mg/m² on Day 1 and Dex 20 mg/body on Days 1-2

4

9

87/F

III/IIIA

BJP

CR

CR

5

15

BD Bor 1.6 mg/m² on Day 1 and Dex 20 mg/body on Days 1-2

7

10

64/F

I/IIIA

BJP

VGPR

VGPR

9

19

BD Bor 1.6 mg/m² on Day 1 and Dex 20 mg/body on Days 1-2

5

11

70/F

III/IIIA

IgG

VGPR

VGPR

0

48

BD Bor 1.6 mg/m² on Day 1 and Dex 20 mg/body on Days 1-2

4

12

63/M

I/IIA

IgA

PR

PD

0

9

BD Bor 1.6 mg/m² on Day 1 and Dex 20 mg/body on Days 1-2

1

13

51/M

III/IIIB

BJP

ND

PD

0

41

BD Bor 1.6 mg/m² on day 1 and Dex 20 mg/body on Days 1-2

5

14

76/F

I/IIA

BJP

ND

PD

1

45

BD Bor 1.6 mg/m² on Day 1 and Dex 20 mg/body on Days 1-2

5

15

44/M

I/IA

IgG

PR

PR

3

27

BDT100 Bor 1.6 mg/m² on Day 1, Dex 20 mg/m² on Days 1-2, and Tha 100 mg/body on Days 1-28

9

16

87/F

III/IIIB

IgG

PR

PR

4

22

BDT50 Bor 1.6 mg/m² on Day 1, Dex 20 mg/body on Days 1-2, and Tha 50 mg/body on Days 1-28

4

17

76/F

III/I

IgG

SD

SD

1

33

BDT50 Bor 1.6 mg/m² on Day 1, Dex 20 mg/body on Days 1-2, and Tha 50 mg/body on Days 1-28

5

18

85/F

II/IIIA

BJP

PR

PR

0

44

BDT50 Bor 1.6 mg/m² on Day 1, Dex 20 mg/body on Days 1-2, and Tha 50 mg/body on Days 1-28

1

19

60/M

III/IIB

IgG

PR

PR

2

26

BDT50 Bor 1.6 mg/m² on Day 1, Dex 20 mg/body on Days 1-2, and Tha 50 mg/body on Days 1-28

17#

20

90/F

I/IIIA

IgG

PR

PR

2

49

BDT50 Bor 1.6 mg/m² on Day 1, Dex 20 mg/body on Days 1-2, and Tha 50 mg/body on Days 1-28

13 #

21

66/M

I/IIIA

BJP

ND

ND

0

25

BDT100 Bor 1.6 mg/m² on Day 1, Dex 20 mg/m² on Days 1-2, and Tha 100 mg/body on Days 1-28

14 #

22

61/F

I/IIIA

IgA

VGPR

PD

2

24

BDL10 Bor 1.6 mg/m² on Day 1, Dex 20 mg/m² on Days 1-2, and Len 10 mg/body on Days 1-28

4