DHEA Experiments

Cell Lines

Mouse cell lines

Rat sub-cultured cells

Human cell lines

Effect on melanoma cell growth

Decreased mouse melanoma cell growth significantly

No significant decrease on human melanoma cell growth

Effect on gastric cancer cell growth

No effect at all on human gastric cancer cell growth

Effect on vascular smooth muscle cell growth

Modeerate decrease in cell growth due to differentiation of cells

Effect on adipogenesis

Decreased 3T3-L1 preadiposcyte differentiation to fat cell and hence decreased adipogenesis

Anabolic action

Promoted differentiation of mouse mesenchymal stem cell line 10T1/2 to myotubes