Days after infection | Total number of macrophages (CD68+) | Number of alternatively activated macrophages (M2) (arginase+) | Number of classically activated macrophages (M1) (iNOS+) | Number of type II pneumocytes (SP-A+) |
1 | 44.5 ± 0.98a | 17.9 ± 1.82a | 21.5 ± 1.7 | 23.1 ± 1.61a |
3 | 52.8 ± 1.36ab | 17.5 ± 1.35a | 26.1 ± 1.5 | 26.2 ± 1.39a |
6 | 39.2 ± 1.2ab | 11.6 ± 1.45ab | 18.2 ± 1.4 | 21.3 ± 0.93ab |
10 | 38.5 ± 1.84a | 7.8 ± 0.89ab | 21.2 ± 0.9 | 22.6 ± 0.95a |
14 | 38.3 ± 1.01a | 7.7 ± 0.60a | 15.5 ± 2.4 | 18.9 ± 1.24ab |
21 | 38.1 ± 1.52a | 9.4 ± 1.56a | 19.9 ± 1 | 26.1 ± 0.89ab |
30 | 39.9 ± 1.08ab | 13.1 ± 1.62ab | 24.8 ± 1.7 | 24.6 ± 1.33a |
control | 10.1 ± 0.96 | 1.3 ± 0.34 | 3.64 ± 0.4 | 4.8 ± 0.65 |