| Aprepitant | Placebo | Δ | 95% CI | P |
N | 34 | 37 |
|
|
|
Any Adverse Event | 17/34 (50%) | 19/37 (51%) | −0.01 | −0.25 to 0.22 | 0.91 |
Any Serious Adverse Eventa | 3/34 (9%) | 2/37 (5%) | 0.03 | −0.09 to 0.15 | 0.57 |
Wound Dehiscence | 2 (6%) | 0 (0%) | 0.06 | −0.04 to 0.20 | 0.23 |
Paresthesia | 2 (6%) | 0 (0%) | 0.06 | −0.04 to 0.20 | 0.23 |
Wound Infection | 7 (21%) | 6 (16%) | 0.04 | −0.14 to 0.22 | 0.63 |
Blood Clot in Leg | 1 (3%) | 0 (0%) | 0.03 | −0.07 to 0.15 | 0.48 |
Bradycardia | 1 (3%) | 0 (0%) | 0.03 | −0.07 to 0.15 | 0.48 |
Chylous Ascites | 1 (3%) | 0 (0%) | 0.03 | −0.07 to 0.15 | 0.48 |
Hospital-Aquired Pneumonia | 1 (3%) | 0 (0%) | 0.03 | −0.07 to 0.15 | 0.48 |
Hot Flashes | 2 (6%) | 1 (3%) | 0.03 | −0.09 to 0.17 | 0.60 |
Nauseab | 2 (6%) | 1 (3%) | 0.03 | −0.09 to 0.17 | 0.60 |
Stomach Pain | 1 (3%) | 0 (0%) | 0.03 | −0.07 to 0.15 | 0.48 |
Valley Fever | 1 (3%) | 0 (0%) | 0.03 | −0.07 to 0.15 | 0.48 |
Anemia | 1 (3%) | 1 (3%) | 0.00 | −0.12 to 0.13 | >0.99 |
Back Pain | 1 (3%) | 1 (3%) | 0.00 | −0.12 to 0.13 | >0.99 |
Clostridium Difficile | 1 (3%) | 1 (3%) | 0.00 | −0.12 to 0.13 | >0.99 |
Constipation | 2 (6%) | 2 (5%) | 0.00 | −0.13 to 0.15 | >0.99 |
Gas Pain | 1 (3%) | 1 (3%) | 0.00 | −0.12 to 0.13 | >0.99 |
Urinary Retention | 1 (3%) | 1 (3%) | 0.00 | −0.12 to 0.13 | >0.99 |
Headache | 1 (3%) | 2 (5%) | −0.02 | −0.16 to 0.10 | >0.99 |
Abdominal Pain | 0 (0%) | 1 (3%) | −0.03 | −0.15 to 0.08 | >0.99 |
Fatigue | 0 (0%) | 1 (3%) | −0.03 | −0.15 to 0.08 | >0.99 |
Fever | 0 (0%) | 1 (3%) | −0.03 | −0.15 to 0.08 | >0.99 |
Intestinal Perforation | 0 (0%) | 1 (3%) | −0.03 | −0.15 to 0.08 | >0.99 |
Itching | 0 (0%) | 1 (3%) | −0.03 | −0.15 to 0.08 | >0.99 |
Joint Pain in Shoulder | 0 (0%) | 1 (3%) | −0.03 | −0.15 to 0.08 | >0.99 |
Oral Thrush | 0 (0%) | 1 (3%) | −0.03 | −0.15 to 0.08 | >0.99 |
Vomitingb | 0 (0%) | 1 (3%) | −0.03 | −0.15 to 0.08 | >0.99 |
Wound Seroma | 0 (0%) | 1 (3%) | −0.03 | −0.15 to 0.08 | >0.99 |
Diarrhea | 0 (0%) | 2 (5%) | −0.05 | −0.18 to 0.05 | 0.49 |
Rash | 0 (0%) | 2 (5%) | −0.05 | −0.18 to 0.05 | 0.49 |
Urinary Tract Infection | 1 (3%) | 6 (16%) | −0.13 | −0.29 to 0.01 | 0.11 |