Aprepitant

Placebo

Δ

95% CI

P

N

34

37

Any Adverse Event

17/34 (50%)

19/37 (51%)

−0.01

−0.25 to 0.22

0.91

Any Serious Adverse Eventa

3/34 (9%)

2/37 (5%)

0.03

−0.09 to 0.15

0.57

Wound Dehiscence

2 (6%)

0 (0%)

0.06

−0.04 to 0.20

0.23

Paresthesia

2 (6%)

0 (0%)

0.06

−0.04 to 0.20

0.23

Wound Infection

7 (21%)

6 (16%)

0.04

−0.14 to 0.22

0.63

Blood Clot in Leg

1 (3%)

0 (0%)

0.03

−0.07 to 0.15

0.48

Bradycardia

1 (3%)

0 (0%)

0.03

−0.07 to 0.15

0.48

Chylous Ascites

1 (3%)

0 (0%)

0.03

−0.07 to 0.15

0.48

Hospital-Aquired Pneumonia

1 (3%)

0 (0%)

0.03

−0.07 to 0.15

0.48

Hot Flashes

2 (6%)

1 (3%)

0.03

−0.09 to 0.17

0.60

Nauseab

2 (6%)

1 (3%)

0.03

−0.09 to 0.17

0.60

Stomach Pain

1 (3%)

0 (0%)

0.03

−0.07 to 0.15

0.48

Valley Fever

1 (3%)

0 (0%)

0.03

−0.07 to 0.15

0.48

Anemia

1 (3%)

1 (3%)

0.00

−0.12 to 0.13

>0.99

Back Pain

1 (3%)

1 (3%)

0.00

−0.12 to 0.13

>0.99

Clostridium Difficile

1 (3%)

1 (3%)

0.00

−0.12 to 0.13

>0.99

Constipation

2 (6%)

2 (5%)

0.00

−0.13 to 0.15

>0.99

Gas Pain

1 (3%)

1 (3%)

0.00

−0.12 to 0.13

>0.99

Urinary Retention

1 (3%)

1 (3%)

0.00

−0.12 to 0.13

>0.99

Headache

1 (3%)

2 (5%)

−0.02

−0.16 to 0.10

>0.99

Abdominal Pain

0 (0%)

1 (3%)

−0.03

−0.15 to 0.08

>0.99

Fatigue

0 (0%)

1 (3%)

−0.03

−0.15 to 0.08

>0.99

Fever

0 (0%)

1 (3%)

−0.03

−0.15 to 0.08

>0.99

Intestinal Perforation

0 (0%)

1 (3%)

−0.03

−0.15 to 0.08

>0.99

Itching

0 (0%)

1 (3%)

−0.03

−0.15 to 0.08

>0.99

Joint Pain in Shoulder

0 (0%)

1 (3%)

−0.03

−0.15 to 0.08

>0.99

Oral Thrush

0 (0%)

1 (3%)

−0.03

−0.15 to 0.08

>0.99

Vomitingb

0 (0%)

1 (3%)

−0.03

−0.15 to 0.08

>0.99

Wound Seroma

0 (0%)

1 (3%)

−0.03

−0.15 to 0.08

>0.99

Diarrhea

0 (0%)

2 (5%)

−0.05

−0.18 to 0.05

0.49

Rash

0 (0%)

2 (5%)

−0.05

−0.18 to 0.05

0.49

Urinary Tract Infection

1 (3%)

6 (16%)

−0.13

−0.29 to 0.01

0.11