Characteristics | All (183) | without a history of HCC (166) a | with a history of HCC (17) b | p a vs. b |
Age (year)* | 68 (18 - 91) | 65 (18 - 91) | 71 (49 - 84) | <0.001 |
Male: Female | 89:94 | 75:91 | 14:3 | <0.001 |
BMI (kg/m2) | 22.6 (14.4 - 37.4) | 22.7 (14.4 - 37.4) | 22.0 (18.6 - 34.9) | NS |
DCV/ASV:SOF/LDV: SOF/RBV:OBV/PTV/rit: EBR/GZR:PIB/GLE | 39:55:42:6:9:32 | 32:52:38:5:8:30 | 7:3:4:0:1:2 | NS |
Duration of the follow-up (months)* | 33.4 (12 - 58.2) | 32.8 (12 - 58.2) | 40.7 (12 - 57.0) | NS |
Previous IFN treatment, Non-responder: Relapse | 15:38 | 15:6 | 0:2 | NS |
DM | 8 | 5 | 3 | NS |
Daily alcohol intake ≥ 40 g/day | 2 | 1 | 1 | NS |
HCV genotype 1:2:3 | 123:58:2 | 85:53:2 | 12:5:0 | NS |
HCV RNA (Log IU/ml)* | 6.2 (2.3 - 7.4) | 6.2 (2.3 - 7.4) | 5.8 (4.5 - 7.3) | NS |
White cell count (/μl)* | 5000 (2100 - 18,000) | 5000 (360 - 10,600) | 4400 (2600 - 18,000) | NS |
Hemoglobin (g/dl)* | 13.5 (7.3 - 17.2) | 13.5 (7.3 - 17.2) | 13.1 (11.0 - 15.4) | NS |
Platelets (104/μl)* | 17.0 (5.2 - 80.9) | 17.3 (5.2 - 68.0) | 11.7 (8.3 - 80.9) | NS |
Aspartate aminotransferase (IU/L)* | 41 (4 - 361) | 39 (4 - 361) | 50 (27 - 213) | NS |
Alanine aminotransferase (IU/L)* | 40 (7 - 472) | 39 (7 - 472) | 51 (21 - 212) | NS |
Total bilirubin (mg/dl)* | 0.73 (0.34 - 5.00) | 0.73 (0.34 - 5.00) | 0.71 (0.5 - 1.84) | NS |
Albumin (g/dl)* | 4.1 (2.2 - 5.2) | 4.1 (2.4 - 5.2) | 3.7 (2.6 - 4.6) | NS |
Creatinine (mg/dl)* | 0.72 (0.45 - 8.69) | 0.70 (0.45 - 8.69) | 0.82 (0.56 - 1.30) | NS |
Alpha-fetoprotein (AFP) (ng/ml)* | ||||
Before | 5.0 (1 - 560) | 4.0 (1 - 450) | 9.0 (1 - 560) | <0.001 |
SVR24 | 4.0 (1 - 133) | 3.0 (1.0 - 19) | 6.0 (10 - 133) | <0.001 |
Fib-4* | 2.82 (0.09 - 5.72) | 2.52 (0.16 - 3.99) | 4.35 (1.52 - 5.06) | <0.001 |
LS0 (kPa)* | 8.0 (2.5 - 40.9) | 7.5 (2.5 - 40.9) | 16.1 (7.3 - 28.0) | <0.05 |
LS24 (kPa)* | 6.0 (2.6 - 31.6) | 5.8 (2.6 - 31.6) | 14.8 (9.9 - 29.1) | <0.01 |
LS48 (kPa)* | 5.3 (2.4 - 29.5) | 5.0 (2.4 - 25.1) | 12.0 (5.3 - 29.5) | <0.001 |
HCC |
| Occurrence 7 | Recurrence 9 |
|