SN	Ligands	Predicted ADME Parameter from SWISSADME
SN	Ligands	MW	MR	TPSA (Å²)	Log P	ESOL Log S	ESOL Class	GIA	BBB permeant	P-gp	CYPs Inhibitor	Log Kp (cm/s)	BS	SA
1	58a	322.79	93.5	55.98	3.81	−4.95	Moderately soluble	High	Yes	Yes	CYP1A2, CYP2C19, CYP2C9, CYP3A4	−5.27	0.55	3.07
2	58b	367.24	96.19	55.98	3.9	−5.26	Moderately soluble	High	Yes	Yes	CYP1A2, CYP2C19, CYP2C9, CYP3A4	−5.5	0.55	3.09
3	58c	306.33	88.45	55.98	3.58	−4.51	Moderately soluble	High	Yes	Yes	CYP1A2, CYP2C19, CYP3A4	−5.55	0.55	3.07
4	58d	352.81	99.99	65.21	3.80	−5.01	Moderately soluble	High	Yes	Yes	CYP1A2, CYP2C19, CYP2C9, CYP3A4	−5.48	0.55	3.14
5	58e	382.84	106.48	74.44	3.77	−5.07	Moderately soluble	High	No	Yes	CYP1A2, CYP2C19, CYP2C9, CYP3A4	−5.68	0.55	3.35
6	58f	357.23	98.51	55.98	4.33	−5.53	Moderately soluble	High	Yes	Yes	CYP1A2, CYP2C19, CYP2C9, CYP3A4	−5.04	0.55	3.09
7	58g	340.78	93.46	55.98	4.11	−5.1	Moderately soluble	High	Yes	Yes	CYP1A2, CYP2C19, CYP2C9, CYP3A4	−5.31	0.55	3.08
8	58h	401.68	101.2	55.98	4.41	−5.85	Moderately soluble	High	Yes	Yes	CYP1A2, CYP2C19, CYP2C9, CYP3A4	−5.26	0.55	3.09
9	58i	340.78	93.46	55.98	4.12	−5.1	Moderately soluble	High	Yes	Yes	CYP1A2, CYP2C19, CYP2C9, CYP3A4	−5.31	0.55	3.08
10	58j	338.79	95.52	76.21	3.37	−4.8	Moderately soluble	High	No	Yes	CYP1A2, CYP2C19, CYP2C9, CYP2D6, CYP3A4	−5.63	0.55	3.05
11	Amsacrine	393.46	113.55	88.7	3.47	−5	Moderately soluble	High	No	No	CYP1A2, CYP2C19, CYP2C9, CYP2D6, CYP3A4	−5.85	0.55	2.94
12	Etoposide	588.56	139.11	160.83	1.15	−3.75	Soluble	Low	No	Yes	CYP2D6	−9.46	0.17	6.27