No | LogP | MR | MV | IC50 (AGS*) (μM) |
1 | −0.35 | 65.36 | 177.7 | 75.2 |
2 | 0.11 | 70.19 | 193.9 | 82.1 |
3 | 0.75 | 94.59 | 240.6 | 2.5 |
4 | 0 | 96.47 | 239 | 15.5 |
5 | 0.7 | 101.26 | 264.6 | 2.8 |
6 | 1.19 | 94.58 | 244.8 | 3 |
7 | 0.64 | 101.26 | 264.6 | 4 |
8 | 0.71 | 94.58 | 244.8 | 5.2 |
9 | 0.95 | 107.94 | 288.6 | 9.1 |
10 | 0.88 | 99.29 | 259.1 | 2.1 |
11 | 1.42 | 103.92 | 275.6 | 3.9 |
12 | 0.99 | 87.57 | 242 | 2.5 |
13 | 0.33 | 87.02 | 237.9 | 4.6 |
14 | 1.46 | 94.77 | 256.2 | NA** |
15 | 2.28 | 109.17 | 284.8 | 2 |
16 | 1.21 | 99.41 | 256.9 | 1 |
17 | 0.46 | 101.29 | 255.3 | 3.3 |
18 | 1.16 | 106.09 | 280.9 | 5.5 |
19 | 1.65 | 99.4 | 261.1 | 1 |
20 | 1.66 | 105.96 | 268.7 | 1 |
21 | 1.1 | 106.09 | 280.9 | >100 |
22 | 1.17 | 99.4 | 261.1 | 1.9 |
23 | 1.41 | 112.77 | 304.9 | 31.7 |
24 | 1.34 | 104.11 | 275.4 | 4.7 |
25 | 1.88 | 108.75 | 291.9 | 19.2 |
26 | 1.45 | 92.19 | 257.7 | 5.2 |
27 | 0.79 | 91.85 | 254.1 | 3.9 |
28 | 1.92 | 99.39 | 271.9 | 2.2 |
29 | 2.74 | 113.79 | 300.4 | 4.2 |