BMC Research Notes

2011, 4:460 [22]

Joint Bone Spine

84, (2017); 113-114 [21]

BMC Research Notes

2017, 10:34 [23]

Study design

Case-control

Case-control

Case-control

Participant number

Cases: Controls

160

80:80

129

43:86

171

57:57:57

Age

Cases: Controls

Both: 20 - 60 years

Cases: Controls

46.5:46.3

RA: PD: Control

42.9:42:30.5

Gender

F:M 9:1

Females were 79% and 75.6% in the cases and controls respectively.

F:M 8.3:1

Country of origin

Sudan

Burkina Faso

Sudan

Inclusion criteria

2010-ACR/EULAR criteria for RA

2010-ACR/EULAR criteria for RA

2010-ACR/EULAR criteria for RA

Exclusion criteria

Pregnancy, lactation, smoking, periodontal therapy or antibiotics in the previous three months, or any systemic condition which might have affected the progression of periodontitis, localized or generalized aggressive periodontitis

Diabetes mellitus, pregnancy, antibiotic therapy and smoking

Systemic diseases that can affect periodontal status, smoking, antibiotic therapy with the last 3 months and periodontal treatment with in the last 6 months

Major findings

No association between the drugs used for treatment of rheumatoid arthritis (Non Steroidal Anti-Inflammatory Drugs & Disease Mordifying Anti-Rheumatic Drugs) and the periodontal parameters (plaque index, gingival index, and clinical attachment loss).

Periodontal disease was not significantly associated with Age ≥ 50 years, male gender, Disease duration ≥ 10 years, DAS28 ≥ 3.2, Joint deformities and ACPA

The was a significant difference in all periodontal parameters among the three groups. The periodontal disease group experienced significantly higher values in all clinical periodontal parameters in comparison to the RA and healthy groups (p ≤ 0.001).