Key inclusion criteria

1. 20 years old or more at the time of informed consent.

2. Agreement with written informed consent.

3. Capable of visiting the hospital regularly

4. Agreement with mixing investigational treatment and existing treatment

5. Agreement with selecting one tooth per disease

6. Following selection criterion

･Caries: dentin caries

･Dental hypersensitivity: pain induced by daily life

･Discolored teeth: desire for whitening

Key exclusion criteria

1. Patients with oral mucosal diseases

2. Past medical history of adverse effects of local anesthetic

3. Pregnancy or possibility of pregnancy

4. Participants of other clinical trials

5. Taking painkillers

6. Patients judged inadequate for this trial by the investigators