Characteristic

1^st sample set (GWAS)

2^nd sample set (Replication)

Total

Cases

Controls

Cases

Controls

Cases

Controls

(n = 396)

(n = 457)

(n = 395)

(n = 798)

(n = 791)

(n = 1255)

Sex, n (%)

Female

247 (62.4)

280 (61.3)

249 (63.0)

453 (56.8)

496 (62.7)

733 (58.4)

Male

149 (37.6)

177 (38.7)

146 (37.0)

345 (43.2)

295 (37.3)

522 (41.6)

Mean age in years (S.D.)

39.0 (12.9)

40.0 (13.1)

37.3 (13.0)

41.2 (14.8)

38.2 (13.0)

40.8 (14.2)