Univariate

Multivariate

Limited disease:^a

HR

95% CI

P

HR

95% CI

P

Gender

Female (n = 49)

1.00

ref

1.00

ref

Male (n = 59)

2.10

1.37 - 3.22

0.0007

2.43

1.45 - 4.06

0.0007

Age

<70 (n = 68)

1.00

ref

1.00

ref

≥70 (n = 40)

1.64

1.08 - 2.48

0.020

1.07

0.64 - 1.77

0.804

Performance status

0-1 (n = 74)

1.00

ref

1.00

ref

2-4 (n = 34)

2.01

1.29 - 3.11

0.002

2.18

1.17 - 4.06

0.014

Extensive disease:^b

Gender

Female (n = 56)

1.00

ref

1.00

ref

Male (n = 102)

1.62

1.15 - 2.28

0.006

1.59

1.12 - 2.26

0.010

Age

<70 (n = 80)

1.00

ref

1.00

ref

≥70 (n = 78)

1.28

0.93 - 1.77

0.133

0.67

0.45 - 0.99

0.046

Performance status

0-1 (n = 42)

1.00

ref

1.00

ref

2-4 (n = 116)

2.42

1.67 - 3.50

<0.001

2.48

1.63 - 3.77

<0.001