Factors Categories	Centralised hospital		Decentralised sites		Total		P-value
Factors Categories	No	%	No	%	No	%	P-value
	812	52.7	730	47.3	1 542	100
Follow-up time in months	26.8 (26.6 - 27.0)
Baseline weight (SD)	53.12 (17.0)
Age, mean (SD)	35.7 (10.8)
Age at diagnosis
18 - 30	303	19.7	245	15.9	548	35.5	0.247
31 - 40	292	18.9	258	16.7	550	35.7
41 - 50	145	9.4	153	9.9	298	19.3
51 or more	72	4.7	74	4.8	146	9.5
Gender
Male	399	25.9	346	22.4	745	48.3	0.264
Female	413	26.8	384	24.9	797	51.7
Previous MDR-TB episodes
No previous MDR-TB episodes	802	52.0	673	43.6	1 475	95.7	<0.001*
1 previous MDR-TB episode	9	0.6	55	3.6	64	4.2
2 or more previous MDR-TB episodes	1	0.1	2	0.1	3	0.2
Type of TB
Pulmonary TB	804	52.1	706	45.8	1 510	97.9	0.001*
Extra-pulmonary TB	8	0.5	24	1.6	32	2.1
Comorbidities Conditions
No other diseases or conditions	780	92.5	9	1.1	789	93.6	<0.001*
Diabetes	10	1.2	10	1.2	20	2.4
Epilepsy	4	0.5	8	1.0	12	1.4
Hearing loss prior to start treatment	1	0.1	10	1.2	11	1.3
Renal problems	0	0	3	0.4	3	0.4
Substance abuse	0	0	4	0.5	4	0.5
Psychiatric problems	4	0.5	0	0	4	0.5
HIV status
Positive	576	39.1	524	35.6	1 100	74.7	0.089**
Negative	211	14.3	162	11.0	373	25.3
Status
Cured	439	28.5	425	27.5	864	56.0	<0.001*
Died	113	7.3	132	8.6	245	15.9
Defaulted	229	14.9	105	6.8	334	21.7
Lost to follow-up	31	2.0	68	4.4	99	6.4