HIV and Aging Parameters

Description

Value/Population Size (=100)

Rationale

a

Rate at which children susceptible to TB become HIV+ TB-susceptible adults

6.15E−05

Aging rate to maintain constant population structure × childhood incidence of HIV

b

Rate at which children susceptible to TB become HIV− adults susceptible to TB

0.071424179

Aging rate to maintain constant population structure ×

(1-childhood incidence of TB)

c

Rate at which HIV− adults susceptible to

TB become HIV+ adults susceptible to TB

0.003234425

Adult HIV incidence (new HIV cases per year/population size)

d

Rate at which children with latent TB become HIV+ adults with latent TB

6.15E−05

Aging rate to maintain constant population structure × childhood incidence of HIV

e

Rate at which children with latent TB become HIV− adults with latent TB

0.071424179

Aging rate to maintain constant population structure × (1-childhood incidence of TB)

f

Rate at which HIV− adults with latent TB become HIV+ adults with latent TB

0.003234425

Adult HIV incidence (new HIV cases per year/population size)

g

Rate at which children with active TB become HIV+ adults with active TB

6.15E−05

Aging rate to maintain constant population structure × childhood incidence of HIV

h

Rate at which children with active TB become HIV− adults with active TB

0.035712089

Aging rate to maintain constant population structure × (1-childhood incidence of TB)/2

i

Rate at which HIV− adults with active TB become HIV+ adults with active TB

0.003234425

Adult HIV incidence (new HIV cases per year/population size)

j

Rate at which adults with HIV− adults with active infectious TB become HIV+ adults with active TB

0.003234425

Adult HIV incidence (new HIV cases per year/population size)

k

Rate at which children with active TB become adults with active infectious TB

0.035712089

Aging rate to maintain constant population structure × (1-childhood incidence of TB)/2

x

HIV mortality rate

0.05

Assumed mortality set to maintain constant population

y

TB mortality rate

0.08

Assumed mortality set to maintain constant population

μ

Background mortality rate

0.03

Assumed mortality set to maintain constant population