| Class | Receptor | Structure | Factor | Target |
| I | Epidermal growth factor receptor (EGFR) | Rich in cysteine nitrogenbase | Epidermal growth factor (EGF) | Mesenchymal and epidermalcells |
| II | Insulin growth factor-1 receptor (IGF-1 R) | Hetero tetramers rich in cysteine | Insulin growth factor (IGF) | Hepatocytes, muscles and other cells |
| III | Platelet derived growth factor receptor (PDGFR) | Has a kinase insert and 3 immunoglobulin domains | Platelet derived growth factor (PDGF) | Mesenchymal and trophoblast |
| IV | Fibro blast Growth factor receptor (FGFR) | Contain acidic domain, kinase insert and 3 immunoglobulins like domain | Fibro blast growth factor (FBF) | Mesenchymal, fibroblast and other cells |
| V | vascular endothelial growth factor (VEGF) receptor | contains kinase insert domain and 7 immunoglobulins | vascular endothelial growth factor (VEGF) | Endothelial and mesenchymal cells |