Parameter

Group I

(n = 25)

Group II

(n = 25)

Test of sig

P

Spleen size (cm)

20.78 ± 4.2

25.10 ± 3.6

t = 3.770

0.001*

Sokal score

1.21 ± 0.342

1.5 ± 0. 36

t = 2.819

0.002*

Sokal risk category

Low risk

Intermediate

High

4 (16%)

10 (40%)

11 (44%)

-

5 (20.8%)

19 (79.2%)

χ² = 7.402

0.023*

BCR-ABL1 at diagnosis (%)

70.37 ± 26.25

73.88 ± 22.85

u = 295.000

0.731

BCR-ABL1 transcript at 3 months (%)

4.53 ± 5.23

35.54 ± 8.13

u = 14.500

0.000*

C480G genotype

CC

CG+GG

17 (51.5%)

8 (47%)

16 (48.5%)

9 (53.0%)

χ² = 0.089

0.765